Dianoxil 50 - 20 comprimidos (50 mg/comprimido)

Dianoxyl 50 (Methandrostenolone or methandienone) is the most recognized trade name for the drug methandrostenolone, also referred to as methandienone in many countries. Methandrostenolone is a derivative of testosterone, modified so that the hormone’s androgenic (masculinizing) properties are reduced and its anabolic (tissue building) properties preserved. Having a lower level of relative androgenicity than testosterone, methandrostenolone is classified as an “anabolic” steroid, although quite a distinct androgenic side is still present. This drug was designed, and is principally sold, as an oral medication, although it can also be found in a number of injectable veterinary solutions. Dianabol is today, and has historically been, the most commonly used oral anabolic/androgenic steroid for physique and performance enhancing purposes. Methandrostenolone or methandienone is a modified form of testosterone. It differs by: 1) the addition of a methyl group at carbon 17- alpha to protect the hormone during oral administration and 2) the introduction of a double bond between carbons 1 and 2, which reduces its relative androgenicity. The resulting steroid also has a much weaker relative binding affinity for the androgen receptor than testosterone, but at the same time displays a much longer half-life and lower affinity for serum-binding proteins in comparison. These features (among others) allow methandrostenolone to be a very potent anabolic steroid in spite of a weaker affinity for receptor binding. Recent studies have additionally confirmed that its primary mode of action involves interaction with the cellular androgen receptor

Estudos demonstraram que tomar um esteróide anabolizante oral com alimentos pode diminuir sua biodisponibilidade. Isso é causado pela natureza solúvel em gordura dos hormônios esteróides, que pode permitir que parte do medicamento se dissolva com a gordura dietética não digerida, reduzindo sua absorção pelo trato gastrointestinal. Para utilização máxima, este esteróide deve ser tomado com o estômago vazio.

The original prescribing guidelines for Dianoxyl 50 called for a daily dosage of 5 mg. This was to be administered on an intermittent basis, with the drug taken for no more than 6 consecutive weeks. Thereafter, a break of 2 to 4 weeks was advised before therapy was resumed. For physique- or performance-enhancing purposes, the drug is also used intermittently, with cycles usually lasting between 6 and 8 weeks in length followed by 6-8 weeks off. Although a low dose of 5 mg daily may be effective for improving performance, athletes typically take much higher amounts. A daily dosage of three to six 5 mg tablets (15-30 mg) is most common, and typically produces very dramatic results. Some venture even higher in dosage, but this practice usually leads to a more profound incidence of side effects, and is generally discouraged. Dianabol stacks well with a variety of other steroids. It is noted to mix particularly well with the mild anabolic Nandroxyl 250, for example. Together one can expect exceptional muscle and strength gains, with side effects not much worse than one would expect from Dianoxyl 50 alone. For sheer mass, a long-acting testosterone ester like enanthate or cypionate can be used. With the high estrogenic/androgenic properties of this androgen, however, side effects should be more pronounced. Gains would be pronounced as well, which usually makes such an endeavor worthwhile to the user. As discussed earlier, ancillary drugs can be added to reduce the side effects associated with this kind of cycle. The half-life of Dianabol is only about 3 to 5 hours. A single daily dosage schedule will produce a varying blood level, with ups and downs throughout the day. The user, likewise, has a choice, to either split up the tablets during the day or to take them all at one time. The usual recommendation has been to divide them and try to regulate the concentration in your blood. This, however, will produce a lower peak blood level than if the tablets were taken all at once, so there may be a trade-off with this option. Both options work fine, but anecdotal evidence seems to support single daily doses as being better for overall results. With such a schedule, it seems logical that taking the pills earlier in the day would be optimal. This would allow a considerable number of daytime hours for an androgen-rich metabolism to heighten the uptake of nutrients, especially the critical hours following training.

Sendo moderadamente androgênico, Dianoxyl 50 é realmente apenas um esteróide popular entre os homens. Quando usado por mulheres, são possíveis fortes sintomas de virilização. Alguns experimentam, no entanto, e muitas vezes consideram doses baixas (2,5-5 mg) deste esteróide bastante eficazes para o crescimento muscular. Estudos demonstraram que a maioria das mulheres notará acne, o que é indicativo de androgenicidade, com uma dosagem de apenas 10 mg por dia. É provável que as crianças notem efeitos virilizantes com apenas 2,5 mg por dia.